cell injury types

Reversible injury	Irreversible injury
§  Generalized cell swelling §  ER swelling §  Cytoplasmic blebs §  Loss of microvilli §  Detachment of ribosomes from endoplasmic reticulum §  Clumping of nuclear chromatin §  Myelin figures	§  ↑cell swelling §  Profound disturbance function §  Lysosomes----Swelling & disruption §  Mitochondria--------swelling & large amorphous densities §  Nuclear changes------ ®      Pyknosis----    nuclear condensation ®      Karyorrhexis-- nuclear fragmentation ®      Karyolysis---- nuclear dissolution §  Decreased basophilia