07/03/2011

About confounding factor in SPM and STATISTICS

Confounding factor/Lurking factor
§  Associated with both the exposure & disease
§  Distributed unequally b/w study & control groups
§  It is itself a risk factor for the disease
§  an extraneous variable in a statistical model that correlates (positively or negatively) with both the dependent variable and the independent variable.
§  It is neutralized by matching
§  Matching------- we select control in such a way that they are similar to cases with regard to confounding factors

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